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Postdoc position in NMR-based mechanistic biochemistry

Postdoc position in NMR-based mechanistic biochemistry

Aarhus UniversityDenmark, DK
Over 30 dage siden
Job beskrivelse

Are you interested in NMR-based structural mechanistic biology and excited at the prospect to contribute to the molecular understanding of the human longevity factor FoxO3? Then the Viennet lab at iNANO invites you to apply for a fulltime Postdoc position funded by the Independent Research Fund Denmark.

Expected start date and duration of employment

This is a –year position from 1 October 2024 or as soon possible thereafter.

Job description

The position will focus on experimental determination of mechanisms underlying the regulation of FoxO3 by phosphorylation. Two main aspects will be investigated, namely the regulation of co-activator binding and DNA interactions.

You will establish protocols and prepare specifically phosphorylated samples of FoxO3, and perform NMR, biophysical and cell biology experiments. The focus can be put on advanced chemical biology routes or advanced dynamics NMR experiments, depending on your interests.

If your interests align, you will contribute to the development of novel tailored NMR methods. You will work closely with international collaborators, including through a research stay abroad at IBS Grenoble or Brown University.

You will present your research at local and international conferences.

Your profile

  • Applicants should hold a PhD in structural biology, chemical biology or similar.
  • Applicants must have good skills in English (oral and written) and be independent, creative, and dependable.
  • Applicants should have several publications in internationally recognized peer-reviewed journals, experience in presenting their work and strong personal and team-work skills. Demonstrated experience working in large collaborative environments and contributing to lab management is a plus.
  • Priority will be given to applicants with a previous experience in NMR OR chemical biology approaches to protein phosphorylation.

Who we are

The Interdisciplinary Nanoscience Center (iNANO; ) at Aarhus University is a modern research and education center with a particular emphasis on collaboration across traditional disciplinary boundaries. iNANO is at the forefront of nanocharacterization and is equipped with state-of-the-art facilities in microscopy, diffraction, spectroscopy and cell culture. The NMR research is also embedded within the Department of Chemistry ().

The Viennet lab in the bioNMR group focuses on elucidating protein regulation by NMR and investigates protein disorder, dynamics and interactions. We are part of the Danish Center for Ultra-high field NMR spectroscopy and have access to NMR spectrometers operating at 500, 700 and 950 MHz for solution NMR, as well as solid-state spectrometers.

More information can be found at :

Aarhus University provides a strong international research and training environment with excellent professional and private conditions. Foreign employees can get help and information from the AU International Center () and Work in Denmark (). Tax reduction schemes for researchers may apply.

What we offer

The iNANO center offers :

  • A well-developed research infrastructure, laboratories and access to shared equipment
  • An exciting interdisciplinary environment with many national, international and industrial collaborators
  • A research climate encouraging lively, open and critical discussion within and across different fields of research
  • A work environment with close working relationships, networking and social activities
  • A workplace characterised by professionalism, equality and a healthy work-life balance.
  • Place of work and area of employment

    The place of work is the iNANO house, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark, and the area of employment is Aarhus University with related departments.

    Contact information